Corporate Site

Find out what makes us the world's largest and most experienced reproductive tissue bank.

SPERMBANK.COM

Apply to become a sperm donor and help make dreams come true

debusa.com

Search for egg donors that are qualified and ready to donate.

Donate-Eggs.com

Apply to become an egg donor and help make dreams come true

CORDBLOOD.COM

Protect your family and bank your baby's stem cells (cord blood & tissue banking)

FERTILE-FUTURE.COM

Preserve your fertility with embryo, sperm and egg cryopreservation and storage

CRIOBANCO.COM

Bienvenido a la versión española de cryobank.com. Encuentra su donante hoy!

Donor Screening

  1. Why does California Cryobank perform a genetic evaluation on donor applicants?
  2. How is a donor's family history information collected and verified?
  3. What is an Extended Profile?
  4. Can genetic testing eliminate the risk for birth defects?
  5. Why doesn't California Cryobank test for all known genetic diseases?
  6. How does California Cryobank determine which genetic tests to perform on its donors?
  7. How does California Cryobank manage a donor if he has positive or abnormal genetic test results?
  8. What genetic testing does California Cryobank currently perform on its donors?  
  9. When are new tests added to the donor qualification process?
  10. How can I find out what genetic tests were performed on the donors in which I am interested?
  11. Can I request that my donor be tested for other genetic conditions?
  12. Should I inform California Cryobank if I have a family history of a particular genetic disorder?
  13. What can I do to reduce the risk for birth defects in my child?
  14. Where can I obtain more information about genetic testing?

  1. Why does California Cryobank perform a genetic evaluation on donor applicants?
    Every woman has a 3 to 4% chance to have a child with a birth defect, regardless of whether she conceives naturally or uses assisted reproductive technologies. It is not possible to eliminate these risks or test for all of them before becoming pregnant. However, a genetic risk assessment is performed on California Cryobank's donor applicants as part of the donor qualification process. The goal of the risk assessment is to try to reduce the risk for significant medical problems in the donor's offspring. If a donor applicant is considered to have an increased risk for having offspring with birth defects, above the 3 to 4% risk in the general population, he is not eligible to participate in our anonymous donor program.
  2. How is a donor's family history information collected and verified?
    At California Cryobank we collect medical information from donor applicants over a two to three month period from the time of their first contact with our company. Information is collected in multiple formats and by several different staff members and reviewed for consistency and accuracy. If we receive information that is incomplete or inconsistent, the applicant will be asked to provide additional information to clarify his family history in order to continue with the program.
  3. What is an Extended Profile
    Extended Profiles include three-generation medical and genetic histories that each donor is required to complete when he enters the donor program. The family members described in the Extended Profile include parents, siblings, grandparents, aunts, uncles and cousins. In addition to medical and genetic information, Extended Profiles provide a variety of personal details including the donor's religion, hobbies, SAT scores, physical characteristics, etc. We strongly recommend that clients review these profiles before making their final donor selection. Genetic counselors can be contacted in the Genetics Department at (877) 743-6384 to answer questions about the medical history reported.
  4. Can genetic testing eliminate the risk for birth defects?
    No. While it is not possible to test any one person for every genetic disorder, genetic testing is performed on our donor applicants for numerous genetic disorders. The genetic testing helps to identify risks or reduce the risk for specific disorders in the donors' offspring but cannot eliminate the risks.
  5. Why doesn't California Cryobank test for all known genetic diseases?
    It is not possible to test anyone for all possible genetic diseases. There are thousands of inherited disorders, and the causes of many of these conditions are currently unknown.
  6. How does California Cryobank decide which genetic tests to perform on its donors?
    In part, we use practice guidelines from the American College of Medical Genetics and Genomics (www.acmg.net), American College of Obstetrics and Gynecology (www.acog.org), and the American Society of Reproductive Medicine (www.asrm.org) to determine the best practices for performing genetic testing on our anonymous sperm donors. We also consider the reliability, utility, as well as the limitations of a particular genetic test when considering it for our program. We currently perform more genetic testing on our sperm donors than is recommended to the general population for routine prenatal or preconception care.
  7. How does California Cryobank manage a donor if he has positive or abnormal genetic test results?
    All people carry mutations for disorders that are inherited in an autosomal recessive manner. If a sperm donor is known to carry a mutation for one or more inherited disorders, this information is made available to all clients on the donor’s Genetic Test Summary (GTS). The donors’ offspring are not at risk to be affected with those conditions unless their biological mothers also carry mutations for the same condition.

    We strongly recommend that all recipients discuss their donor’s Genetic Test Summary with their healthcare providers prior to using that donor’s vials, in order to determine if the donor’s results are suitable for their personal reproductive plans.

    PLEASE NOTE: A normal or negative result indicates that the test did not detect any clinically significant genetic mutations or abnormalities for those specific conditions. Genetic testing can reduce the chance for specific inherited conditions in a donor’s offspring but it cannot eliminate the risks for those specific disorders or other untested conditions. In addition, there is always a 3 to 4% chance to have a child with a medical issue, regardless of the screening performed.
  8. What genetic testing does California Cryobank currently perform on its donors?


    Expanded Genetic Testing

    DNA Advantage Donors are screened for over 260 genetic conditions, including cystic fibrosis and spinal muscular atrophy. We also perform a hemoglobin evaluation and chromosome analysis. See below for information about some of these specific tests and conditions.

    Since the availability of genetic testing has changed over time, each donor has had different genetic testing. Please download and discuss your donor’s Genetic Test Summary (GTS) with your personal healthcare providers to verify that the donor is suitable for your needs.

    Cystic Fibrosis Carrier Screening
    Cystic fibrosis (CF) is a chronic illness that typically involves severe lung disease and gastrointestinal problems. People with CF often have a shortened lifespan. Cystic fibrosis is inherited in an autosomal recessive manner which means that both parents have to carry mutations for CF to be at risk of having a child affected with this disorder. CF occurs most often among individuals of Caucasian ancestry; approximately 1 out of every 25 healthy Northern European or Ashkenazi Jewish individuals carries a mutation for CF. Carrier screening for cystic fibrosis is performed by analyzing the donor's DNA for common mutations or changes in the gene for CF. CF carrier screening is performed on all of CCB's sperm donor applicants, regardless of the donor's ancestry.

    Hemoglobin Evaluation
    Hemoglobin is the molecule that carries oxygen to the cells of our bodies. Hemoglobin disorders are inherited in an autosomal recessive manner. This means that a child must inherit mutations from both parents to be at risk of developing a disorder such as alpha-thalassemia, beta-thalassemia, or sickle cell anemia. A hemoglobin evaluation on our donor applicants includes a complete blood count (CBC) which evaluates the size, shape, and number of a person's blood cells. In addition, a test called a hemoglobin fractionation is performed to detect many, but not all, clinically significant differences in a person's hemoglobin.

    • Alpha-Thalassemia and Beta-Thalassemia
      Individuals who are affected with thalassemia generally have severe anemia and may require frequent blood transfusions and other medical interventions over the course of their lifetimes. Some types of thalassemia may result in a shortened lifespan; more severe forms may result in fetal demise or death in infancy. Alpha-thalassemia occurs most often among individuals of Asian or African ancestry. Beta-thalassemia (also known as Cooley's anemia or Mediterranean anemia) occurs most often among people of Mediterranean descent.
    • Sickle Cell Anemia
      Hemoglobin S is the hemoglobin that is found in abnormal amounts in a person who is affected with sickle cell anemia. Sickle cell anemia causes painful episodes of joint and bone pain and increased risks for strokes, infections, and organ damage. Approximately 1out of every 10 individuals of African descent carries a mutation for sickle cell anemia.

    Chromosome Analysis
    Chromosomes are the structures that carry our DNA. A chromosome analysis looks at the number and the structure of an individual’s chromosomes. Typically, an analysis of human chromosomes reveals a total of 46 chromosomes. If a sperm donor applicant has an abnormal chromosome numbers or structure he would not be eligible to participate in our program.

    Spinal Muscular Atrophy Carrier Screening
    Spinal muscular atrophy is a progressive neuromuscular disease that results in muscle wasting and, in its most common and severe form, death due to respiratory failure before two years of age. SMA is inherited in an autosomal recessive manner which means that both parents must be carriers of mutations for SMA to be at risk of having a child affected with this disorder. Approximately 1 out of every 50 individuals in the general population carries a mutation for SMA.

     
  9. When are new tests added to the donor qualification process?
    Genetic tests and technologies are continuously being developed and improved. These new developments may lead to changes in the genetic testing that we perform on our sperm donor applicants. In most cases when we add new genetic tests to our screening process, the tests are performed on new donor applicants. The new tests are not performed on retired donors. Therefore, not every donor who has vials available for purchase has had exactly the same genetic testing.
  10. How can I find out what genetic tests were performed on the donors in which I am interested?
    A Genetic Test Summary tells you which specific tests were performed on a donor and the results of those tests. You can learn more about the information on a GTS here or by contacting one of our genetic counselors. Our genetic counselors are available to discuss the tests performed on your donor as well as the test limitations and additional testing options that you may want to consider. For more information please contact the Genetics Department at 877-743-6384.
  11. Can I request that my donor be tested for other genetic conditions?
    Special requests for genetic testing are accommodated whenever possible. If you have a family history or carry a mutation for a particular condition and there is a medical risk to your offspring, we will contact your donor and determine if he is available for additional testing. For more information, please contact the Genetics Department at 877-743-6384. Please see our Special Testing Information Sheet for more details.
  12. Should I inform California Cryobank if I have a family history of a particular genetic disorder?
    Yes! In some cases, if you have a personal or family history of a genetic condition, the genetic testing performed on our donors may not be sufficient for your pregnancy. Special testing may be available on your donor of interest. If you have a positive genetic test result or a family history of a genetic disease, please contact our Genetics Department at 877-743-6384 to obtain information about special testing options that may be available for your situation.
  13. What can I do to reduce the risk for birth defects in my child?
    Although we screen our donors to help reduce the risk for medical issues in donor offspring, it is important for all clients to speak with their physician and/or genetic counselor about their own family histories. A child inherits 50% of his or her DNA from each parent. Many clients may not know that they have an increased risk to have a child with medical problems unless they have a thorough family history evaluation. CCB recommends that all clients meet with a genetic counselor to evaluate their own family medical histories and discuss genetic testing options that are appropriate for their needs. You can locate a genetic counselor in your area at www.nsgc.org.
  14. Where can I obtain more information about genetic testing?
    For more information please contact our Genetics Department at 877-743-6384.

Your Cart


{{vialItem.TypeDetailStr}}
{{vialItem.availabilityCopy}} {{vialItem.phone}}
Price:
${{vialItem.Price}}
Qty:
Subtotal:
${{(vialItem.Quantity * vialItem.Price)}}

Total ({{cartCont.totalVials}} Vials)
${{cartCont.totalValue}}
Add {{ (cartCont.familyTodayMinVials - cartCont.totalVials) }} vial(s) to qualify for free storage!
Low vial alert: Final inventory for this donor
{{cartCont.message}}

Vials aren't guaranteed until you complete checkout.

Your Cart Is Empty

Important: Vials sell out quickly. Availability is not guaranteed until checkout is completed.

Need Help?
Browse our Most Recent Donors
Try our Purchasing Faqs
HOW MANY VIALS DO I NEED?

National averages range from 3-4 insemination cycles per successful pregnancy. We recommend purchasing at least 5 vials per child to guarantee your donor remains available until reaching your personal family goals. Additionally, you get 1 Year FREE storage if you purchase 4 or more vials ($475 value).

WHY SHOULD I THINK ABOUT STORING VIALS?

Our donors sell out and retire quickly! We have thousands of clients forced to choose between a new donor or not having a second child because they chose not to store vials for future use while they were available. To help you plan for your future, we offer 3 Years FREE storage if you purchase 3 Years+ vials ($1,050 value) - as well as the ability to sell back any unused vials that have not left our control.

;